SCREENING PREGNANT WOMEN AND THEIR NEONATES FOR ILLICIT DRUG USE: CONSIDERATION OF THE INTEGRATED TECHNICAL, MEDICAL, ETHICAL, LEGAL, AND SOCIAL ISSUES

North America is currently suffering from one of the worst epidemics of illicit drug use in recent history: the opioid crisis.Pregnant women are not immune to the ravages of substance misuse which affects themselves, their pregnancies, and the wider community.The prevalence of drug misuse in pregnancy is not well quantified due to the lack of good

Abstract Background Mechanical ventilation (MV) is a key component in the care of critically ill and injured patients.Weaning from MV constitutes a major challenge in intensive care units (ICUs).Any delay in weaning may increase the number of complications and leads to greater expense.Nurse-led, protocol-directed weaning has become popular, but it

Synthetic aperture radar (SAR), which can work normally under various meteorological conditions, has been widely researched and applied in marine vessel target monitoring and identification.Among the many research topics, due to the inconsistency of ship scale in SAR images, susceptibility to sea and land noise and clutter interference, resulting i

We study how functional constraints bound and shape evolution through an analysis of mammalian voltage-gated sodium channels.The primary function of sodium channels is to allow the propagation of action potentials.Since Hodgkin and Huxley, mathematical models have suggested that sodium channel properties need to be tightly constrained for catherine

Abstract Background Small cell lung cancer (SCLC) is an aggressive neuroendocrine grahams c+ eczema & dermatitis cream cancer with an appalling overall survival of less than 5% (Zimmerman et al.J Thor Oncol 14:768-83, 2019).Patients typically respond to front line platinum-based doublet chemotherapy, but almost universally relapse with drug resista